• A new framework for assessing subject-specific whole brain circulation and perfusion using MRI-based measurements and a multi-scale continuous flow model 

      Hodneland, Erlend; Hanson, Erik Andreas; Sævareid, Ove; Nævdal, Geir; Lundervold, Arvid; Solteszova, Veronika; Zanna, Antonella; Deistung, Andreas; Reichenbach, Jürgen; Nordbotten, Jan Martin (Peer reviewed; Journal article, 2019)
      A large variety of severe medical conditions involve alterations in microvascular circulation. Hence, measurements or simulation of circulation and perfusion has considerable clinical value and can be used for diagnostics, ...
    • Automated segmentation of endometrial cancer on MR images using deep learning 

      Hodneland, Erlend; Dybvik, Julie Andrea; Wagner-Larsen, Kari Strøno; Solteszova, Veronika; Zanna, Antonella; Fasmer, Kristine Eldevik; Krakstad, Camilla; Lundervold, Arvid; Lundervold, Alexander Selvikvåg; Salvesen, Øyvind; Erickson, Bradley J.; Haldorsen, Ingfrid S (Peer reviewed; Journal article, 2021)
      Preoperative MR imaging in endometrial cancer patients provides valuable information on local tumor extent, which routinely guides choice of surgical procedure and adjuvant therapy. Furthermore, whole-volume tumor analyses ...
    • Mathematics and Medicine: How mathematics, modelling and simulations can lead to better diagnosis and treatments 

      Hanson, Erik Andreas; Hodneland, Erlend; Lorentzen, Rolf Johan; Nævdal, Geir; Nordbotten, Jan Martin; Sævareid, Ove; Zanna, Antonella (Peer reviewed; Journal article, 2019)
      Starting with the discovery of X-rays by Röntgen in 1895, the progress in medical imaging has been extraordinary and immensely beneficial to diagnosis and therapy. Parallel to the increase of imaging accuracy, there is the ...
    • Perfusion estimation using synthetic MRI-based measurements and a porous media flow model 

      Lorentzen, Rolf Johan; Nævdal, Geir; Sævareid, Ove; Hodneland, Erlend; Hanson, Erik Andreas; Munthe-Kaas, Antonella Zanna (Peer reviewed; Journal article, 2023)
      The measurement of perfusion and filtration of blood in biological tissue give rise to important clinical parameters used in diagnosis, follow-up, and therapy. In this paper, we address techniques for perfusion analysis ...
    • RadEx: Integrated visual exploration of multiparametric studies for radiomic tumor profiling 

      Mörth, Eric; Wagner-Larsen, Kari Strøno; Hodneland, Erlend; Krakstad, Camilla; Haldorsen, Ingfrid S.; Bruckner, Stefan; Smit, Noeska Natasja (Peer reviewed; Journal article, 2020)
      Better understanding of the complex processes driving tumor growth and metastases is critical for developing targeted treatment strategies in cancer. Radiomics extracts large amounts of features from medical images which ...
    • The association of PTSD symptom severity with amygdala nuclei volumes in traumatized youths 

      Ousdal, Olga Therese; Milde, Anne Marita; Hafstad, Gertrud Sofie; Hodneland, Erlend; Dyb, Grete; Craven, Alexander R.; Melinder, Annika Maria D; Endestad, Tor; Hugdahl, Kenneth (Peer reviewed; Journal article, 2020)
      The amygdala is a core component in neurobiological models of stress and stress-related pathologies, including post-traumatic stress disorder (PTSD). While numerous studies have reported increased amygdala activity following ...
    • Well-posedness and discretization for a class of models for mixed-dimensional problems with high-dimensional gap 

      Hodneland, Erlend; Hu, Xiaozhe; Nordbotten, Jan Martin (Journal article; Peer reviewed, 2021)
      In this work, we show the underlying mathematical structure of mixed-dimensional models arising from the composition of graphs and continuous domains. Such models are becoming popular in applications, in particular, to ...
    • Whole-volume tumor MRI radiomics for prognostic modeling in endometrial cancer 

      Fasmer, Kristine Eldevik; Hodneland, Erlend; Dybvik, Julie Andrea; Wagner-Larsen, Kari Strøno; Trovik, Jone; Salvesen, Øyvind; Krakstad, Camilla; Haldorsen, Ingfrid S. (Peer reviewed; Journal article, 2020)
      Background In endometrial cancer (EC), preoperative pelvic MRI is recommended for local staging, while final tumor stage and grade are established by surgery and pathology. MRI‐based radiomic tumor profiling may aid in ...